Therapeutic antibody in the skin
dOFM was successfully used to measure a therapeutic antibody (secukinumab) and inflammatory markers in healthy and lesional skin of patients with psoriasis
Bioequivalence of drugs in the skin
In an FDA (Food and Drug Administration) co-funded project we have developed a methodology to determine bioequivalence of topical drugs
PK of nanoformulated cancer drugs in the brain
cOFM was successfully used to measure substance transport enhanced by nanocarriers across the blood-brain barrier
Tissue selective insulin concentrations in adipose tissue
aOFM was successfully used to measure insulin concentrations and time-resolved profiles in a clinical trial
